Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 8 subunit alpha' and Ligand = 'BDBM373840'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 8 subunit alpha (Homo sapiens (Human))	BDBM373840 ((S)-2-fluoro-4-((1-((2-isopropylthiazol-4-yl)methy...) Show SMILES CC(C)c1nc(CN2CC[C@@H](C2)N(C)c2cc(F)c(cc2C)S(=O)(=O)Nc2cscn2)cs1 |r| Show InChI InChI=1S/C22H28FN5O2S3/c1-14(2)22-25-16(11-32-22)9-28-6-5-17(10-28)27(4)19-8-18(23)20(7-15(19)3)33(29,30)26-21-12-31-13-24-21/h7-8,11-14,17,26H,5-6,9-10H2,1-4H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. US Patent					Assay Description In general, Trex HEK293 cells were stably transfected with an inducible expression vector containing the full-length cDNA coding for the desired huma...				US Patent US10815229 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WTS
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Homo sapiens (Human))	BDBM373840 ((S)-2-fluoro-4-((1-((2-isopropylthiazol-4-yl)methy...) Show SMILES CC(C)c1nc(CN2CC[C@@H](C2)N(C)c2cc(F)c(cc2C)S(=O)(=O)Nc2cscn2)cs1 |r| Show InChI InChI=1S/C22H28FN5O2S3/c1-14(2)22-25-16(11-32-22)9-28-6-5-17(10-28)27(4)19-8-18(23)20(7-15(19)3)33(29,30)26-21-12-31-13-24-21/h7-8,11-14,17,26H,5-6,9-10H2,1-4H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2HM5BRC
					More data for this Ligand-Target Pair