Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM145592'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM145592 (US8952169, 390) Show SMILES CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)CCC2(CC2)CC1 Show InChI InChI=1S/C23H31FN2O4S/c1-22(5-7-23(8-6-22)9-10-23)15-30-20-14-19(24)18(13-17(20)16-3-4-16)21(27)25-31(28,29)26-11-2-12-26/h13-14,16H,2-12,15H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Xenon Pharmaceuticals Inc.; Genentech, Inc. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...				US Patent US8952169 (2015) BindingDB Entry DOI: 10.7270/Q2M04445
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM145592 (US8952169, 390) Show SMILES CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)CCC2(CC2)CC1 Show InChI InChI=1S/C23H31FN2O4S/c1-22(5-7-23(8-6-22)9-10-23)15-30-20-14-19(24)18(13-17(20)16-3-4-16)21(27)25-31(28,29)26-11-2-12-26/h13-14,16H,2-12,15H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	37
Xenon Pharmaceuticals Inc.; Genentech, Inc. US Patent					Assay Description Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...				US Patent US8952169 (2015) BindingDB Entry DOI: 10.7270/Q2M04445
					More data for this Ligand-Target Pair