BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM176526'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176526
PNG
(US9120752, 58 | US9765029, 58)
Show SMILES OC[C@@H](O)c1cc(nc(c1)-c1ccc(Oc2ccc(F)cc2)cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1cccc(c1)C#N |r|
Show InChI InChI=1S/C31H27FN4O6S/c32-24-6-10-26(11-7-24)42-25-8-4-22(5-9-25)28-17-23(30(38)20-37)18-29(34-28)31(39)35-12-14-36(15-13-35)43(40,41)27-3-1-2-21(16-27)19-33/h1-11,16-18,30,37-38H,12-15,20H2/t30-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.31E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)


BindingDB Entry DOI: 10.7270/Q2FX7CKS
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176526
PNG
(US9120752, 58 | US9765029, 58)
Show SMILES OC[C@@H](O)c1cc(nc(c1)-c1ccc(Oc2ccc(F)cc2)cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1cccc(c1)C#N |r|
Show InChI InChI=1S/C31H27FN4O6S/c32-24-6-10-26(11-7-24)42-25-8-4-22(5-9-25)28-17-23(30(38)20-37)18-29(34-28)31(39)35-12-14-36(15-13-35)43(40,41)27-3-1-2-21(16-27)19-33/h1-11,16-18,30,37-38H,12-15,20H2/t30-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.31E+3n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair