Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM231255 (US9346798, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.83 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description HEK 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro auto... | US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM231255 (US9346798, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 38.6 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy... | US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM231255 (US9346798, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress method | Bioorg Med Chem Lett 24: 3690-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.038 BindingDB Entry DOI: 10.7270/Q2KS6VJM | |||||||||||
More data for this Ligand-Target Pair |