Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM275792'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM275792 (N-(azetidin-1- ylsulfonyl)-5-chloro- 4-(4-chloro-3...) Show SMILES Fc1cc(Oc2ccc(Cl)c(c2)C(F)(F)F)c(Cl)cc1C(=O)NS(=O)(=O)N1CCC1 Show InChI InChI=1S/C17H12Cl2F4N2O4S/c18-12-3-2-9(6-11(12)17(21,22)23)29-15-8-14(20)10(7-13(15)19)16(26)24-30(27,28)25-4-1-5-25/h2-3,6-8H,1,4-5H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.2	n/a
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...				US Patent US10071957 (2018) BindingDB Entry DOI: 10.7270/Q2J1056P
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM275792 (N-(azetidin-1- ylsulfonyl)-5-chloro- 4-(4-chloro-3...) Show SMILES Fc1cc(Oc2ccc(Cl)c(c2)C(F)(F)F)c(Cl)cc1C(=O)NS(=O)(=O)N1CCC1 Show InChI InChI=1S/C17H12Cl2F4N2O4S/c18-12-3-2-9(6-11(12)17(21,22)23)29-15-8-14(20)10(7-13(15)19)16(26)24-30(27,28)25-4-1-5-25/h2-3,6-8H,1,4-5H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80.7	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...				US Patent US10071957 (2018) BindingDB Entry DOI: 10.7270/Q2J1056P
					More data for this Ligand-Target Pair