Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50300204 ((2R)-2-acetylamino-N-benzyl-3-methoxypropanamide |...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents | DrugBank PDB Article PubMed | n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human inactivated voltage-gated Na channel 1.7 expressed in HEK293 cells by patch-clamp technique | J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50300204 ((2R)-2-acetylamino-N-benzyl-3-methoxypropanamide |...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents | DrugBank PDB | n/a | n/a | 1.82E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombin | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |