Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM141245'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM141245 (US8653100, 139) Show SMILES CCCS(=O)(=O)NCCOc1ccc2CCNC(c2c1)C(C)(C)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H31ClN2O3S/c1-4-15-30(27,28)26-13-14-29-20-10-5-17-11-12-25-22(21(17)16-20)23(2,3)18-6-8-19(24)9-7-18/h5-10,16,22,25-26H,4,11-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
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