Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM160584'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM160584 (US9045459, 1) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CCc2ccc(cc2C1)C(CN)Cc1ccccc1 Show InChI InChI=1S/C22H26N4O2S/c1-25-15-22(24-16-25)29(27,28)26-10-9-18-7-8-19(12-21(18)14-26)20(13-23)11-17-5-3-2-4-6-17/h2-8,12,15-16,20H,9-11,13-14,23H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9045459 (2015) BindingDB Entry DOI: 10.7270/Q28914M9
					More data for this Ligand-Target Pair