Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM162236'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM162236 (US9051280, 194) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CC[C@@H](CN)[C@@H](Cc3ccccc3)c2c1 |r| Show InChI InChI=1S/C24H30N4O3S/c1-28-16-24(26-17-28)32(29,30)27-11-12-31-21-10-9-19-7-8-20(15-25)22(23(19)14-21)13-18-5-3-2-4-6-18/h2-6,9-10,14,16-17,20,22,27H,7-8,11-13,15,25H2,1H3/t20-,22+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9051280 (2015) BindingDB Entry DOI: 10.7270/Q2930RXN
					More data for this Ligand-Target Pair