Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM202311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM202311 (US9238619, 47) Show SMILES CCOC(=O)N1CC(Cc2ccccc2)(C1)c1cccc(OCCNS(=O)(=O)c2cn(C)cn2)c1 Show InChI InChI=1S/C25H30N4O5S/c1-3-33-24(30)29-17-25(18-29,15-20-8-5-4-6-9-20)21-10-7-11-22(14-21)34-13-12-27-35(31,32)23-16-28(2)19-26-23/h4-11,14,16,19,27H,3,12-13,15,17-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F
					More data for this Ligand-Target Pair