Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50011171'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50011171 (CHEMBL3259920) Show SMILES CN1CCCC(C1)(NC(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C20H21F3N2O/c1-25-13-5-12-19(14-25,16-6-3-2-4-7-16)24-18(26)15-8-10-17(11-9-15)20(21,22)23/h2-4,6-11H,5,12-14H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human GlyT1 expressed in cells assessed as [3H]glycine uptake				ACS Med Chem Lett 5: 428-33 (2014) Article DOI: 10.1021/ml500005m BindingDB Entry DOI: 10.7270/Q2FF3TWV
					More data for this Ligand-Target Pair