Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50175946'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50175946 (8-[(cis, rac)-2-(3,4-dichloro-phenyl)-2-hydroxy-cy...) Show SMILES O[C@]1(CCCC[C@H]1N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H29Cl2N3O2/c26-20-10-9-18(16-21(20)27)25(32)11-5-4-8-22(25)29-14-12-24(13-15-29)23(31)28-17-30(24)19-6-2-1-3-7-19/h1-3,6-7,9-10,16,22,32H,4-5,8,11-15,17H2,(H,28,31)/t22-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	173	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]glycine from human GlyT1 by radiometric assay				Bioorg Med Chem Lett 16: 354-7 (2005) Article DOI: 10.1016/j.bmcl.2005.09.067 BindingDB Entry DOI: 10.7270/Q2P26XPX
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