Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50178415'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50178415 ((2S)-2-((2-(4,5-dichloro-6-methoxy-1,3-dioxo-2-phe...) Show SMILES COc1cc2C(=O)C(CCN(C)[C@@H](C)C(O)=O)(C(=O)c2c(Cl)c1Cl)c1ccccc1 Show InChI InChI=1S/C22H21Cl2NO5/c1-12(21(28)29)25(2)10-9-22(13-7-5-4-6-8-13)19(26)14-11-15(30-3)17(23)18(24)16(14)20(22)27/h4-8,11-12H,9-10H2,1-3H3,(H,28,29)/t12-,22?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of uptake of [14C]glycine into human JAR cells expressing human GlyT1				Bioorg Med Chem Lett 16: 1388-91 (2006) Article DOI: 10.1016/j.bmcl.2005.11.041 BindingDB Entry DOI: 10.7270/Q29C6X13
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