Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50178425'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50178425 (2-((3-(1,3-dioxo-2-phenyl-2,3-dihydro-1H-inden-2-y...) Show SMILES CN(CCCC1(C(=O)c2ccccc2C1=O)c1ccccc1)CC(O)=O Show InChI InChI=1S/C21H21NO4/c1-22(14-18(23)24)13-7-12-21(15-8-3-2-4-9-15)19(25)16-10-5-6-11-17(16)20(21)26/h2-6,8-11H,7,12-14H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of uptake of [14C]glycine into human JAR cells expressing human GlyT1				Bioorg Med Chem Lett 16: 1388-91 (2006) Article DOI: 10.1016/j.bmcl.2005.11.041 BindingDB Entry DOI: 10.7270/Q29C6X13
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