Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50460375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50460375 (CHEMBL4225641) Show SMILES CCN1CC2CC1(C2)C(NC(=O)c1c(C)cccc1C)c1ccccc1 |(25.68,-27.98,;27.16,-27.5,;27.49,-25.97,;26.44,-24.81,;27.22,-23.46,;28.75,-23.78,;28.91,-25.33,;27.62,-24.96,;30.27,-26.11,;30.27,-27.64,;31.6,-28.42,;32.92,-27.65,;31.6,-29.96,;30.26,-30.71,;28.91,-29.93,;30.26,-32.25,;31.59,-33.03,;32.92,-32.25,;32.92,-30.71,;34.27,-29.93,;31.59,-25.34,;31.59,-23.8,;32.92,-23.04,;34.26,-23.81,;34.26,-25.34,;32.92,-26.11,)| Show InChI InChI=1S/C23H28N2O/c1-4-25-15-18-13-23(25,14-18)21(19-11-6-5-7-12-19)24-22(26)20-16(2)9-8-10-17(20)3/h5-12,18,21H,4,13-15H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1 expressed in CHO cells assessed as reduction in [3H]glycine uptake pretreated for 15 mins followed by [3H]glyci...				Bioorg Med Chem Lett 28: 1043-1049 (2018) Article DOI: 10.1016/j.bmcl.2018.02.029 BindingDB Entry DOI: 10.7270/Q26112ZK
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