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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50099866'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Rattus norvegicus)		BDBM50099866
PNG
(CHEMBL418388 | Sodium; (E)-2-amino-5-(3,4-diethyl-...)
Show SMILES CCc1ccc(cc1CC)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F
Show InChI InChI=1S/C21H23F2NO2/c1-3-13-5-6-15(11-14(13)4-2)17(9-10-20(24)21(25)26)18-8-7-16(22)12-19(18)23/h5-9,11-12,20H,3-4,10,24H2,1-2H3,(H,25,26)/p-1/b17-9+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 660n/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...

Bioorg Med Chem Lett 11: 1371-3 (2001)


BindingDB Entry DOI: 10.7270/Q20C4W9Q
More data for this
Ligand-Target Pair