BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50099870'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Rattus norvegicus)		BDBM50099870
PNG
(CHEMBL29022 | Sodium; (E)-2-amino-5-biphenyl-2-yl-...)
Show SMILES NC(C\C=C(\c1ccc(F)cc1F)c1ccccc1-c1ccccc1)C([O-])=O
Show InChI InChI=1S/C23H19F2NO2/c24-16-10-11-20(21(25)14-16)19(12-13-22(26)23(27)28)18-9-5-4-8-17(18)15-6-2-1-3-7-15/h1-12,14,22H,13,26H2,(H,27,28)/p-1/b19-12+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.75E+3n/an/an/an/an/an/a



NPS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...

Bioorg Med Chem Lett 11: 1371-3 (2001)


BindingDB Entry DOI: 10.7270/Q20C4W9Q
More data for this
Ligand-Target Pair