Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50448005'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50448005 (CHEMBL3115229) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CC2CCC(NC(=O)c3ccc(Cl)c(Cl)c3)C2C1 Show InChI InChI=1S/C18H20Cl2N4O3S/c1-23-9-17(21-10-23)28(26,27)24-7-12-3-5-16(13(12)8-24)22-18(25)11-2-4-14(19)15(20)6-11/h2,4,6,9-10,12-13,16H,3,5,7-8H2,1H3,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GlyT2 (unknown origin) assessed as [14C]-glycine transport				Bioorg Med Chem Lett 24: 1062-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.011 BindingDB Entry DOI: 10.7270/Q2XD1350
					More data for this Ligand-Target Pair