Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50448012'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50448012 (CHEMBL3115223) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CC2CCC(NC(=O)c3ccc(F)cc3F)C2C1 Show InChI InChI=1S/C18H20F2N4O3S/c1-23-9-17(21-10-23)28(26,27)24-7-11-2-5-16(14(11)8-24)22-18(25)13-4-3-12(19)6-15(13)20/h3-4,6,9-11,14,16H,2,5,7-8H2,1H3,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GlyT2 (unknown origin) assessed as [14C]-glycine transport				Bioorg Med Chem Lett 24: 1062-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.011 BindingDB Entry DOI: 10.7270/Q2XD1350
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