BindingDB PrimarySearch

Found 73 hits Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM22418'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	68.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse--Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from dopamine transporter of rat brain membrane				Bioorg Med Chem Lett 14: 3295-8 (2004) Article DOI: 10.1016/j.bmcl.2004.03.075 BindingDB Entry DOI: 10.7270/Q2F76D43
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by PDSP K_i Database									J Pharmacol Exp Ther 289: 1229-36 (1999) BindingDB Entry DOI: 10.7270/Q2TX3CWQ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by PDSP K_i Database									J Pharmacol Exp Ther 293: 686-96 (2000) BindingDB Entry DOI: 10.7270/Q2H993QF
Wake Forest University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35248 from dopamine transporter (DAT) of rat striatal membrane				Bioorg Med Chem Lett 11: 2079-83 (2001) BindingDB Entry DOI: 10.7270/Q28P6114
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by PDSP K_i Database									J Pharmacol Exp Ther 293: 686-96 (2000) BindingDB Entry DOI: 10.7270/Q2H993QF
Wake Forest University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mercer University Curated by PDSP K_i Database									J Pharmacol Exp Ther 301: 527-35 (2002) Article DOI: 10.1124/jpet.301.2.527 BindingDB Entry DOI: 10.7270/Q2C53JFB
Mercer University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from dopamine transporter of rat caudate putamen tissue				Bioorg Med Chem Lett 12: 2387-90 (2002) BindingDB Entry DOI: 10.7270/Q2X067KS
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Inhibition of DAT (unknown origin) expressed in COS7 cells assessed as reduction in [3H]DA uptake incubated for 5 mins by beta-scintillation counting...				J Med Chem 59: 10676-10691 (2016) Article DOI: 10.1021/acs.jmedchem.6b01373 BindingDB Entry DOI: 10.7270/Q2WQ05RV
National Institute on Drug Abuse Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Displacement of [3H]WIN35,428 from wild type human DAT expressed in COS7 cell membranes incubated for >90 mins by radioligand binding assay				J Med Chem 59: 10676-10691 (2016) Article DOI: 10.1021/acs.jmedchem.6b01373 BindingDB Entry DOI: 10.7270/Q2WQ05RV
National Institute on Drug Abuse Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)				Bioorg Med Chem Lett 9: 3325-8 (2000) BindingDB Entry DOI: 10.7270/Q2RB754D
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity uptake of [3H]DA using rat nerve endings obtained from brain regions enriched in DAT.				Bioorg Med Chem Lett 11: 2079-83 (2001) BindingDB Entry DOI: 10.7270/Q28P6114
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA reuptake at dopamine transporter in rat striatum				Bioorg Med Chem Lett 12: 993-5 (2002) BindingDB Entry DOI: 10.7270/Q20K294R
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Affinity to inhibit [3H]DA uptake				Bioorg Med Chem Lett 13: 513-7 (2003) BindingDB Entry DOI: 10.7270/Q2CJ8F1D
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	272	n/a	n/a	n/a	267	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
Research Triangle Institute					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	272	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cells				Bioorg Med Chem Lett 13: 2151-4 (2003) BindingDB Entry DOI: 10.7270/Q2DN45K3
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes				Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description ability to displace [3H]- Mazindol binding to cocaine binding sites on Dopamine transporter of rat striatal membranes				Bioorg Med Chem Lett 10: 1443-6 (2000) BindingDB Entry DOI: 10.7270/Q2CZ37PP
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	301	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes)				Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	371	-36.3	n/a	n/a	303	n/a	n/a	7.4	22
Human BioMolecular Research Institute					Assay Description Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...				J Med Chem 52: 1530-9 (2009) Article DOI: 10.1021/jm8010993 BindingDB Entry DOI: 10.7270/Q2MK6B7M
Human BioMolecular Research Institute					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	419	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake in HEK cells expressing human SERT				Bioorg Med Chem Lett 13: 4133-7 (2003) BindingDB Entry DOI: 10.7270/Q2DJ5G67
Organix Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporter				Bioorg Med Chem Lett 9: 3325-8 (2000) BindingDB Entry DOI: 10.7270/Q2RB754D
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit high affinity uptake of [3H]DA into rat striatal membrane				Bioorg Med Chem Lett 10: 1443-6 (2000) BindingDB Entry DOI: 10.7270/Q2CZ37PP
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	423	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to inhibit reuptake of dopamine ([3H]DA) at dopamine transporter of rat striatum				Bioorg Med Chem Lett 13: 3565-9 (2003) BindingDB Entry DOI: 10.7270/Q26110WV
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN 35428 from human DAT transiently expressed in COS7 cells				J Med Chem 63: 2343-2357 (2020) Article DOI: 10.1021/acs.jmedchem.9b01188 BindingDB Entry DOI: 10.7270/Q2QF8XD6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from Dopamine transporter of rat caudate membranes				Bioorg Med Chem Lett 12: 2225-8 (2002) BindingDB Entry DOI: 10.7270/Q2DZ08T2
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	475	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by PDSP K_i Database									J Pharmacol Exp Ther 293: 686-96 (2000) BindingDB Entry DOI: 10.7270/Q2H993QF
Wake Forest University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	478	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Synapse 39: 32-41 (2001) Article DOI: 10.1002/1098-2396(20010101)39:1 BindingDB Entry DOI: 10.7270/Q2NV9GT3
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U316 Curated by PDSP K_i Database									J Pharmacol Exp Ther 282: 467-74 (1997) BindingDB Entry DOI: 10.7270/Q2X928VC
INSERM U316 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Industri A/S Curated by PDSP K_i Database									Eur J Pharmacol 166: 493-504 (1989) Article DOI: 10.1016/0014-2999(89)90363-4 BindingDB Entry DOI: 10.7270/Q28C9TR3
Novo Industri A/S Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addit...				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	743	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (MOUSE)	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Concentration required to inhibit binding of ICAM-1 to LFA-1 (Leukocyte function-associated antigen-1), evaluated ELISA				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (BOVINE)	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description In vitro inhibitory activity towards [3H]cocaine binding to rat striatal tissue				J Med Chem 34: 702-5 (1991) BindingDB Entry DOI: 10.7270/Q2X34Z21
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35065-2 binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding at dopamine transporter was determined				J Med Chem 46: 1775-94 (2003) Article DOI: 10.1021/jm030092d BindingDB Entry DOI: 10.7270/Q2FF3T3J
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligand				Bioorg Med Chem Lett 7: 2559-2564 (1997) Article DOI: 10.1016/S0960-894X(97)10053-1 BindingDB Entry DOI: 10.7270/Q2M61KQ3
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Ability to inhibit binding of [3H]WIN-35428 to dopamine transporter in rat caudate putamen				Bioorg Med Chem Lett 11: 823-7 (2001) BindingDB Entry DOI: 10.7270/Q2PN965H
Universit£ di Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporter				Bioorg Med Chem Lett 8: 3689-92 (1999) BindingDB Entry DOI: 10.7270/Q22Z162N
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Macaca fascicularis)	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamen				Bioorg Med Chem Lett 9: 857-62 (1999) BindingDB Entry DOI: 10.7270/Q26D5TGQ
Organix Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428l binding to Dopamine transporter				J Med Chem 35: 2497-500 (1992) BindingDB Entry DOI: 10.7270/Q2736RJC
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to Dopamine transporter in rat striatal membranes.				J Med Chem 35: 135-40 (1992) BindingDB Entry DOI: 10.7270/Q2FQ9X7M
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair

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