Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM364393'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM364393 (US10913711, Compound 2x | US11555013, Compound 2x ...) Show SMILES Brc1ccc(cc1)C(SCC(=O)NCCCc1ccccc1)c1ccc(Br)cc1 Show InChI InChI=1S/C24H23Br2NOS/c25-21-12-8-19(9-13-21)24(20-10-14-22(26)15-11-20)29-17-23(28)27-16-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-15,24H,4,7,16-17H2,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	238	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysis				J Med Chem 57: 1000-13 (2014) Article DOI: 10.1021/jm401754x BindingDB Entry DOI: 10.7270/Q2JM2DMK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM364393 (US10913711, Compound 2x | US11555013, Compound 2x ...) Show SMILES Brc1ccc(cc1)C(SCC(=O)NCCCc1ccccc1)c1ccc(Br)cc1 Show InChI InChI=1S/C24H23Br2NOS/c25-21-12-8-19(9-13-21)24(20-10-14-22(26)15-11-20)29-17-23(28)27-16-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-15,24H,4,7,16-17H2,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ST7TRG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM364393 (US10913711, Compound 2x | US11555013, Compound 2x ...) Show SMILES Brc1ccc(cc1)C(SCC(=O)NCCCc1ccccc1)c1ccc(Br)cc1 Show InChI InChI=1S/C24H23Br2NOS/c25-21-12-8-19(9-13-21)24(20-10-14-22(26)15-11-20)29-17-23(28)27-16-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-15,24H,4,7,16-17H2,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES US Patent					Assay Description Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...				US Patent US10913711 (2021) BindingDB Entry DOI: 10.7270/Q2F47S7B
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM364393 (US10913711, Compound 2x | US11555013, Compound 2x ...) Show SMILES Brc1ccc(cc1)C(SCC(=O)NCCCc1ccccc1)c1ccc(Br)cc1 Show InChI InChI=1S/C24H23Br2NOS/c25-21-12-8-19(9-13-21)24(20-10-14-22(26)15-11-20)29-17-23(28)27-16-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-15,24H,4,7,16-17H2,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rheinische Friedrich-Wilhelms-Universitat Bonn					Assay Description Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...				J Med Chem 48: 7688-707 (2005) BindingDB Entry DOI: 10.7270/Q2PR7Z87
					More data for this Ligand-Target Pair