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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM388489'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM388489
PNG
(US9944618, Compound ID No. 23)
Show SMILES CNC[C@@H]([C@H](OCC(=O)N1CCOCC1)c1ccccc1)c1ccc2ccccc2c1 |r|
Show InChI InChI=1S/C26H30N2O3/c1-27-18-24(23-12-11-20-7-5-6-10-22(20)17-23)26(21-8-3-2-4-9-21)31-19-25(29)28-13-15-30-16-14-28/h2-12,17,24,26-27H,13-16,18-19H2,1H3/t24-,26-/m1/s1
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PC cid
PC sid
UniChem
US Patent
 65.6n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...

Bioorg Med Chem Lett 19: 1164-7 (2009)


BindingDB Entry DOI: 10.7270/Q26D5WBR
More data for this
Ligand-Target Pair