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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50250556'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM50250556
PNG
(CHEMBL4066469)
Show SMILES [O-][S+](Cc1cccs1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H14Cl2OS2/c19-15-7-3-13(4-8-15)18(14-5-9-16(20)10-6-14)23(21)12-17-2-1-11-22-17/h1-11,18H,12H2
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of re-uptake of [3H]-dopamine at human DAT expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured a...

J Med Chem 60: 9330-9348 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01313
BindingDB Entry DOI: 10.7270/Q26112RW
More data for this
Ligand-Target Pair