Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50292470'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50292470 (CHEMBL447018 | Dimethylpseudoxandrine) Show SMILES COc1cc2CCN(C)[C@@H]3Cc4ccc(OC)c(c4)-c4cc(ccc4OC)C(=O)[C@H]4N(C)CCc5cc(OC)c(OC)c(Oc1cc23)c45 |r| Show InChI InChI=1S/C39H42N2O7/c1-40-14-12-23-19-32(45-5)33-21-26(23)29(40)17-22-8-10-30(43-3)27(16-22)28-18-25(9-11-31(28)44-4)37(42)36-35-24(13-15-41(36)2)20-34(46-6)38(47-7)39(35)48-33/h8-11,16,18-21,29,36H,12-15,17H2,1-7H3/t29-,36+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometry				J Nat Prod 58: 1475-1484 (1995) Article DOI: 10.1021/np50124a001 BindingDB Entry DOI: 10.7270/Q2XK8FKW
					More data for this Ligand-Target Pair