Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50304391 ((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cells | Bioorg Med Chem 17: 6890-7 (2009) Article DOI: 10.1016/j.bmc.2009.08.025 BindingDB Entry DOI: 10.7270/Q2X34ZC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50304391 ((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cells | Bioorg Med Chem 17: 6890-7 (2009) Article DOI: 10.1016/j.bmc.2009.08.025 BindingDB Entry DOI: 10.7270/Q2X34ZC2 | |||||||||||
More data for this Ligand-Target Pair |