BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50013068'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50013068
PNG
(CHEMBL3261708)
Show SMILES COc1ccc(cc1C(F)(F)F)C(=O)Nc1ccc(OC(CCN(C)C)c2ccccc2)cc1
Show InChI InChI=1S/C26H27F3N2O3/c1-31(2)16-15-23(18-7-5-4-6-8-18)34-21-12-10-20(11-13-21)30-25(32)19-9-14-24(33-3)22(17-19)26(27,28)29/h4-14,17,23H,15-16H2,1-3H3,(H,30,32)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 22n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis

Bioorg Med Chem Lett 24: 2118-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.043
BindingDB Entry DOI: 10.7270/Q2G44RV5
More data for this
Ligand-Target Pair