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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50128384'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50128384
PNG
((S)-1-[4-(6-Fluoro-benzo[b]thiophen-2-yl)-piperidi...)
Show SMILES Cc1cc2c(OC[C@@H](O)CN3CCC(CC3)c3cc4ccc(F)cc4s3)cccc2[nH]1
Show InChI InChI=1S/C25H27FN2O2S/c1-16-11-21-22(27-16)3-2-4-23(21)30-15-20(29)14-28-9-7-17(8-10-28)24-12-18-5-6-19(26)13-25(18)31-24/h2-6,11-13,17,20,27,29H,7-10,14-15H2,1H3/t20-/m0/s1
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PC sid
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Patents

Similars
PubMed
 11n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]-paroxetine as radioligand

Bioorg Med Chem Lett 13: 1903-5 (2003)


BindingDB Entry DOI: 10.7270/Q2PV6JR6
More data for this
Ligand-Target Pair