Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50136134 (4-[(Naphthalen-1-yloxy)-phenyl-methyl]-piperidine ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
FAES FARMA S A Curated by ChEMBL | Assay Description Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar rats | J Med Chem 46: 5512-32 (2003) Article DOI: 10.1021/jm0309349 BindingDB Entry DOI: 10.7270/Q2QF8TMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50136134 (4-[(Naphthalen-1-yloxy)-phenyl-methyl]-piperidine ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
FAES FARMA S A Curated by ChEMBL | Assay Description Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar rats | J Med Chem 46: 5512-32 (2003) Article DOI: 10.1021/jm0309349 BindingDB Entry DOI: 10.7270/Q2QF8TMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50136134 (4-[(Naphthalen-1-yloxy)-phenyl-methyl]-piperidine ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
FAES FARMA S A Curated by ChEMBL | Assay Description Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar rats | J Med Chem 46: 5512-32 (2003) Article DOI: 10.1021/jm0309349 BindingDB Entry DOI: 10.7270/Q2QF8TMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50136134 (4-[(Naphthalen-1-yloxy)-phenyl-methyl]-piperidine ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair |