BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50198225'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50198225
PNG
(2-((2-methoxybenzyloxy)(3-iodophenyl)methyl)morpho...)
Show SMILES COc1ccccc1COC(C1CNCCO1)c1cccc(I)c1 |w:11.17,10.10|
Show InChI InChI=1S/C19H22INO3/c1-22-17-8-3-2-5-15(17)13-24-19(18-12-21-9-10-23-18)14-6-4-7-16(20)11-14/h2-8,11,18-19,21H,9-10,12-13H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 351n/an/an/an/an/an/an/an/a



Institute for Degenerative Diseases

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from SERT in brain membranes

Bioorg Med Chem Lett 17: 533-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.018
BindingDB Entry DOI: 10.7270/Q2WS8SX8
More data for this
Ligand-Target Pair