Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50203945 ((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5HT from human SERT expressed in HEK293 cells | Bioorg Med Chem Lett 17: 2022-5 (2007) Article DOI: 10.1016/j.bmcl.2007.01.020 BindingDB Entry DOI: 10.7270/Q20R9P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50203945 ((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells | Bioorg Med Chem Lett 18: 2896-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.082 BindingDB Entry DOI: 10.7270/Q2ZG6T44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50203945 ((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]5HT uptake at human 5HT transporter expressed in HEK293 cells | Bioorg Med Chem Lett 18: 596-9 (2008) BindingDB Entry DOI: 10.7270/Q2DR2WBX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50203945 ((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation counting | Bioorg Med Chem Lett 18: 4308-11 (2008) Article DOI: 10.1016/j.bmcl.2008.06.078 BindingDB Entry DOI: 10.7270/Q2Q2401S | |||||||||||
More data for this Ligand-Target Pair |