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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50252117'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM50252117
PNG
(3-((dimethylamino)methyl)-4-(4-(methylthio)phenylt...)
Show SMILES CSc1ccc(Sc2ccc(cc2CN(C)C)S(N)(=O)=O)cc1
Show InChI InChI=1S/C16H20N2O2S3/c1-18(2)11-12-10-15(23(17,19)20)8-9-16(12)22-14-6-4-13(21-3)5-7-14/h4-10H,11H2,1-3H3,(H2,17,19,20)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells

Bioorg Med Chem Lett 18: 4018-21 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.001
BindingDB Entry DOI: 10.7270/Q2W37W4X
More data for this
Ligand-Target Pair