BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50313260'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50313260 (CHEMBL1086613 \| N-(3-(4-(2,3-Dimethylphenyl)pipera...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35.9	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assay				Bioorg Med Chem Lett 20: 1705-11 (2010) Article DOI: 10.1016/j.bmcl.2010.01.093 BindingDB Entry DOI: 10.7270/Q2SN093C
Green Cross Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50313260 (CHEMBL1086613 \| N-(3-(4-(2,3-Dimethylphenyl)pipera...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]imipramine from human SERT expressed in HEK293 cells				Bioorg Med Chem 18: 6156-69 (2010) Article DOI: 10.1016/j.bmc.2010.06.037 BindingDB Entry DOI: 10.7270/Q2W0964C
Green Cross Corporation Curated by ChEMBL					More data for this Ligand-Target Pair