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Found 1 hit Enz. Inhib. hit(s) with Target = 'Solute carrier family 12 member 5' and Ligand = 'BDBM50387293'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 12 member 5


(Homo sapiens (Human))		BDBM50387293
PNG
(CHEMBL2048858)
Show SMILES CCCN1C(N)C(C(=O)CSc2nnc(Cc3ccccc3)o2)C(=O)N(C)C1=O
Show InChI InChI=1S/C19H23N5O4S/c1-3-9-24-16(20)15(17(26)23(2)19(24)27)13(25)11-29-18-22-21-14(28-18)10-12-7-5-4-6-8-12/h4-8,15-16H,3,9-11,20H2,1-2H3
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n/an/a 640n/an/an/an/an/an/a



Vanderbilt University School of Medicine

Curated by ChEMBL


Assay Description
Antagonist activity at KCC2 expressed in human HEK293 cells assessed as decrease in Tl-stimulated fluorescence increase after 8 mins by fluorescence ...

Bioorg Med Chem Lett 22: 4532-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.126
BindingDB Entry DOI: 10.7270/Q26T0NQ1
More data for this
Ligand-Target Pair