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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 2' and Ligand = 'BDBM330061'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 2


(Homo sapiens (Human))		BDBM330061
PNG
((1R,4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-...)
Show SMILES C[C@H]1C[C@@H]2C[C@H]1N1[C@H]2Cn2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O |TLB:0:1:7.6:4,THB:8:7:1.2:4,29:6:1.2:4|
Show InChI InChI=1S/C22H21F2N3O4/c1-10-4-12-5-16(10)27-17(12)9-26-8-14(19(28)20(29)18(26)22(27)31)21(30)25-7-11-2-3-13(23)6-15(11)24/h2-3,6,8,10,12,16-17,29H,4-5,7,9H2,1H3,(H,25,30)/t10-,12+,16+,17-/m0/s1
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PC cid
PC sid
UniChem
US Patent
n/an/a 450n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...

US Patent US9663528 (2017)


BindingDB Entry DOI: 10.7270/Q24F1SVF
More data for this
Ligand-Target Pair