Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 22 member 2 (RAT) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | PubMed | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of TEA uptake in OCT2-expressing MDCK cells | Pharm Res 18: 1528-34 (2001) BindingDB Entry DOI: 10.7270/Q28G8N0T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (Homo sapiens (Human)) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytes | DNA Cell Biol 16: 871-81 (1997) Article DOI: 10.1089/dna.1997.16.871 BindingDB Entry DOI: 10.7270/Q2R2148R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cells | J Pharmacol Exp Ther 303: 959-68 (2002) Article DOI: 10.1124/jpet.102.038885 BindingDB Entry DOI: 10.7270/Q28W3FTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.67E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition pramipexole uptake in rOCT2-injected oocytes | Drug Metab Dispos 33: 495-9 (2005) Article DOI: 10.1124/dmd.104.002519 BindingDB Entry DOI: 10.7270/Q24B32KW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cells | J Pharmacol Exp Ther 303: 959-68 (2002) Article DOI: 10.1124/jpet.102.038885 BindingDB Entry DOI: 10.7270/Q28W3FTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (Mus musculus) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes | Biochem Biophys Res Commun 296: 644-50 (2002) BindingDB Entry DOI: 10.7270/Q2P84D6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM39344 (4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Anatomy of the Bayerische Julius-Maximilians-Universit£t Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes | Am J Physiol Renal Physiol 281: 454-68 (2001) Article DOI: 10.1152/ajprenal.2001.281.3.F454 BindingDB Entry DOI: 10.7270/Q2BR8TF3 | |||||||||||
More data for this Ligand-Target Pair |