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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 2' and Ligand = 'BDBM50420178'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 2


(RAT)
BDBM50420178
PNG
(GUANIDINE)
Show SMILES NC(N)=N
Show InChI InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
UniProtKB/SwissProt

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MCE
MMDB
PC cid
PC sid
PDB
UniChem
PubMed
2.80E+5n/an/an/an/an/an/an/an/a



University of Heidelberg

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT2-expressing HEK293 cells


Mol Pharmacol 56: 1-10 (1999)


BindingDB Entry DOI: 10.7270/Q2KK9D21
More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(RAT)
BDBM50420178
PNG
(GUANIDINE)
Show SMILES NC(N)=N
Show InChI InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
UniProtKB/SwissProt

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MCE
MMDB
PC cid
PC sid
PDB
UniChem
PubMed
7.14E+5n/an/an/an/an/an/an/an/a



Kyoto University Hospital

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (basolateral to cell) in OCT2-expressing MDCK cells


J Pharmacol Exp Ther 287: 800-5 (1998)


BindingDB Entry DOI: 10.7270/Q2D79CQ4
More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(RAT)
BDBM50420178
PNG
(GUANIDINE)
Show SMILES NC(N)=N
Show InChI InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
UniProtKB/SwissProt

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DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 1.71E+5n/an/an/an/an/an/a



Institute of Anatomy of the Bayerische Julius-Maximilians-Universit£t

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytes


Am J Physiol Renal Physiol 281: 454-68 (2001)


Article DOI: 10.1152/ajprenal.2001.281.3.F454
BindingDB Entry DOI: 10.7270/Q2BR8TF3
More data for this
Ligand-Target Pair