BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sonic hedgehog protein' and Ligand = 'BDBM50421177'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sonic hedgehog protein


(Mus musculus (Mouse))		BDBM50421177
PNG
(CHEMBL2086782)
Show SMILES CCCCCC[C@](O)([C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)c1ccccc1 |r|
Show InChI InChI=1S/C32H50O3/c1-4-5-6-10-17-32(35,22-11-8-7-9-12-22)29-14-13-25-24-21-28(34)27-20-23(33)15-18-30(27,2)26(24)16-19-31(25,29)3/h7-9,11-12,23-29,33-35H,4-6,10,13-21H2,1-3H3/t23-,24-,25-,26-,27+,28-,29-,30+,31-,32+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Fate Therapeutics

Curated by ChEMBL


Assay Description
Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assay

Bioorg Med Chem Lett 22: 5893-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.073
BindingDB Entry DOI: 10.7270/Q2WH2R9R
More data for this
Ligand-Target Pair