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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sorbitol dehydrogenase' and Ligand = 'BDBM50108740'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sorbitol dehydrogenase


(Homo sapiens (Human))		BDBM50108740
PNG
(CHEMBL148935 | {4-[4-(4,6-Dichloro-[1,3,5]triazin-...)
Show SMILES OCc1nccc(n1)N1CCN(CC1)c1nc(Cl)nc(Cl)n1
Show InChI InChI=1S/C12H13Cl2N7O/c13-10-17-11(14)19-12(18-10)21-5-3-20(4-6-21)9-1-2-15-8(7-22)16-9/h1-2,22H,3-7H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 490n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Concentration required for 50% in vitro inhibition in sheep liver sorbitol dehydrogenase (s-SDH)

J Med Chem 45: 511-28 (2002)


BindingDB Entry DOI: 10.7270/Q2R210QX
More data for this
Ligand-Target Pair