Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Sortilin' and Ligand = 'BDBM159123'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sortilin (Homo sapiens (Human))	BDBM159123 (US10195186, Example 11 | US9682967, 11) Show SMILES Cc1ccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)nc1C Show InChI InChI=1S/C15H12Cl2N2O3/c1-7-3-4-13(18-8(7)2)19-14(20)9-5-11(16)12(17)6-10(9)15(21)22/h3-6H,1-2H3,(H,21,22)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	457	n/a	480	n/a	n/a	n/a	n/a	7.4	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US9682967 (2017) BindingDB Entry DOI: 10.7270/Q22805SC
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159123 (US10195186, Example 11 | US9682967, 11) Show SMILES Cc1ccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)nc1C Show InChI InChI=1S/C15H12Cl2N2O3/c1-7-3-4-13(18-8(7)2)19-14(20)9-5-11(16)12(17)6-10(9)15(21)22/h3-6H,1-2H3,(H,21,22)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	457	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159123 (US10195186, Example 11 | US9682967, 11) Show SMILES Cc1ccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)nc1C Show InChI InChI=1S/C15H12Cl2N2O3/c1-7-3-4-13(18-8(7)2)19-14(20)9-5-11(16)12(17)6-10(9)15(21)22/h3-6H,1-2H3,(H,21,22)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair