Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingomyelin phosphodiesterase' and Ligand = 'BDBM50370154'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingomyelin phosphodiesterase (Homo sapiens)	BDBM50370154 (CHEMBL4175453) Show SMILES Cc1csc(n1)-c1c(oc2cc(O)c(C)cc2c1=O)C(F)(F)F Show InChI InChI=1S/C15H10F3NO3S/c1-6-3-8-10(4-9(6)20)22-13(15(16,17)18)11(12(8)21)14-19-7(2)5-23-14/h3-5,20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assay				Eur J Med Chem 151: 389-400 (2018) Article DOI: 10.1016/j.ejmech.2018.03.065 BindingDB Entry DOI: 10.7270/Q21R6T2M
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