Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50069663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50069663 (CHEMBL3402532) Show SMILES CCc1nnc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)n1CC Show InChI InChI=1S/C20H23ClN4O2S/c1-3-19-22-23-20(25(19)4-2)18(14-15-8-6-5-7-9-15)24-28(26,27)17-12-10-16(21)11-13-17/h5-13,18,24H,3-4,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity against S1P1R in human U2OS cells expressing beta-arrestin/green fluorescent protein assessed as effect on S1P-induced beta-arres...				Bioorg Med Chem Lett 25: 2041-5 (2015) Article DOI: 10.1016/j.bmcl.2015.03.095 BindingDB Entry DOI: 10.7270/Q22F7Q3D
					More data for this Ligand-Target Pair