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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 2' and Ligand = 'BDBM50178357'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine kinase 2


(Homo sapiens (Human))		BDBM50178357
PNG
(CHEMBL3814603)
Show SMILES Oc1cccc(c1)C(=O)N\N=C\c1cccc(OCc2ccccc2C(F)(F)F)c1
Show InChI InChI=1S/C22H17F3N2O3/c23-22(24,25)20-10-2-1-6-17(20)14-30-19-9-3-5-15(11-19)13-26-27-21(29)16-7-4-8-18(28)12-16/h1-13,28H,14H2,(H,27,29)/b26-13+
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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged full length human recombinant SPHK2 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure...

Bioorg Med Chem 24: 3218-30 (2016)


Article DOI: 10.1016/j.bmc.2016.05.047
BindingDB Entry DOI: 10.7270/Q2377BN8
More data for this
Ligand-Target Pair