Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Squalene synthase (Rattus norvegicus) | BDBM50059865 (4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against microsomal squalene synthase | J Med Chem 34: 1912-4 (1991) Checked by Author BindingDB Entry DOI: 10.7270/Q2S75GXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50059865 (4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against squalene synthase using rat liver microsomal assay | Bioorg Med Chem Lett 7: 3039-3044 (1997) Article DOI: 10.1016/S0960-894X(97)10133-0 BindingDB Entry DOI: 10.7270/Q2XG9RNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50059865 (4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity measured against rat squalene synthase(SQS) enzyme | Bioorg Med Chem Lett 3: 2541-2546 (1993) Article DOI: 10.1016/S0960-894X(01)80713-7 BindingDB Entry DOI: 10.7270/Q26Q1XQP | |||||||||||
More data for this Ligand-Target Pair |