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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Squalene synthase' and Ligand = 'BDBM50288124'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Squalene synthase


(Rattus norvegicus)		BDBM50288124
PNG
(Benzyl-{2-[4-((E)-styryl)-phenoxy]-ethyl}-amine | ...)
Show SMILES C(COc1ccc(\C=C\c2ccccc2)cc1)NCc1ccccc1
Show InChI InChI=1S/C23H23NO/c1-3-7-20(8-4-1)11-12-21-13-15-23(16-14-21)25-18-17-24-19-22-9-5-2-6-10-22/h1-16,24H,17-19H2/b12-11+
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PC cid
PC sid
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Article
n/an/a 9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay

Bioorg Med Chem Lett 6: 2491-2494 (1996)


Article DOI: 10.1016/0960-894X(96)00470-2
BindingDB Entry DOI: 10.7270/Q21V5DZZ
More data for this
Ligand-Target Pair