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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM132191'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Steroid 17-alpha-hydroxylase/17,20 lyase


(Homo sapiens (Human))
BDBM132191
PNG
(USRE45173, 130A)
Show SMILES Cc1ccncc1N1CCCN(C1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C20H19N3O/c1-15-9-10-21-14-19(15)23-12-4-11-22(20(23)24)18-8-7-16-5-2-3-6-17(16)13-18/h2-3,5-10,13-14H,4,11-12H2,1H3
PDB

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PC cid
PC sid
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US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...


US Patent USRE45173 (2014)


BindingDB Entry DOI: 10.7270/Q2MW2FT2
More data for this
Ligand-Target Pair