Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM50358198'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50358198 (CHEMBL1921982) Show SMILES CCNC(=O)c1ccc2cc(ccc2c1)C1(O)CCn2cncc12 Show InChI InChI=1S/C19H19N3O2/c1-2-21-18(23)15-4-3-14-10-16(6-5-13(14)9-15)19(24)7-8-22-12-20-11-17(19)22/h3-6,9-12,24H,2,7-8H2,1H3,(H,21,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of Sprague-Dawley rat testicular microsomal CYP17A1 using [1,2-3H]-17a-hydroxyprogesterone as substrate after 15 m...				Bioorg Med Chem 19: 6383-99 (2011) Article DOI: 10.1016/j.bmc.2011.08.066 BindingDB Entry DOI: 10.7270/Q2X63NDF
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50358198 (CHEMBL1921982) Show SMILES CCNC(=O)c1ccc2cc(ccc2c1)C1(O)CCn2cncc12 Show InChI InChI=1S/C19H19N3O2/c1-2-21-18(23)15-4-3-14-10-16(6-5-13(14)9-15)19(24)7-8-22-12-20-11-17(19)22/h3-6,9-12,24H,2,7-8H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of 17,20-lyase activity of human CYP17A1				Bioorg Med Chem 19: 6383-99 (2011) Article DOI: 10.1016/j.bmc.2011.08.066 BindingDB Entry DOI: 10.7270/Q2X63NDF
					More data for this Ligand-Target Pair