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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50003820'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50003820
PNG
(2-(2,2-Diethoxy-ethylsulfanyl)-4,5-diphenyl-1H-imi...)
Show SMILES CCOC(CSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)OCC
Show InChI InChI=1S/C21H24N2O2S/c1-3-24-18(25-4-2)15-26-21-22-19(16-11-7-5-8-12-16)20(23-21)17-13-9-6-10-14-17/h5-14,18H,3-4,15H2,1-2H3,(H,22,23)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
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PubMed
n/an/a 250n/an/an/an/an/an/a



Rhone-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsome

J Med Chem 35: 4384-92 (1992)


BindingDB Entry DOI: 10.7270/Q218374H
More data for this
Ligand-Target Pair