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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50003831'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50003831
PNG
(4-(3-Chloro-phenyl)-5-phenyl-2-(tetrahydro-pyran-2...)
Show SMILES Clc1cccc(c1)-c1[nH]c(SCC2CCCCO2)nc1-c1ccccc1
Show InChI InChI=1S/C21H21ClN2OS/c22-17-10-6-9-16(13-17)20-19(15-7-2-1-3-8-15)23-21(24-20)26-14-18-11-4-5-12-25-18/h1-3,6-10,13,18H,4-5,11-12,14H2,(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 560n/an/an/an/an/an/a



Rhone-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsome

J Med Chem 35: 4384-92 (1992)


BindingDB Entry DOI: 10.7270/Q218374H
More data for this
Ligand-Target Pair