Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50285428'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50285428 (1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...) Show SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(nc3ccccc23)C(C)C)[nH]c1-c1ccc(OC)cc1 Show InChI InChI=1S/C32H36N4O2S/c1-22(2)31-33-27-10-6-7-11-28(27)36(31)20-8-5-9-21-39-32-34-29(23-12-16-25(37-3)17-13-23)30(35-32)24-14-18-26(38-4)19-15-24/h6-7,10-19,22H,5,8-9,20-21H2,1-4H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assay				Bioorg Med Chem Lett 5: 177-180 (1995) Article DOI: 10.1016/0960-894X(95)00003-C BindingDB Entry DOI: 10.7270/Q2PG1RQJ
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Mus musculus)	BDBM50285428 (1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...) Show SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(nc3ccccc23)C(C)C)[nH]c1-c1ccc(OC)cc1 Show InChI InChI=1S/C32H36N4O2S/c1-22(2)31-33-27-10-6-7-11-28(27)36(31)20-8-5-9-21-39-32-34-29(23-12-16-25(37-3)17-13-23)30(35-32)24-14-18-26(38-4)19-15-24/h6-7,10-19,22H,5,8-9,20-21H2,1-4H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture				Bioorg Med Chem Lett 5: 177-180 (1995) Article DOI: 10.1016/0960-894X(95)00003-C BindingDB Entry DOI: 10.7270/Q2PG1RQJ
					More data for this Ligand-Target Pair