Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sterol O-acyltransferase 1 (Mus musculus) | BDBM50450361 (CHEMBL300913) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a | |
The DuPont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture | Bioorg Med Chem Lett 5: 173-6 (1995) BindingDB Entry DOI: 10.7270/Q2T72HDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50450361 (CHEMBL300913) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 6.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
The DuPont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes | Bioorg Med Chem Lett 5: 173-6 (1995) BindingDB Entry DOI: 10.7270/Q2T72HDT | |||||||||||
More data for this Ligand-Target Pair |